During adolescence, young girls experience the beginning of the menstrual cycle, which not only comes as an uninvited guest, but also brings a worsening case of asthma along with it sometimes as an unwanted friend. While this type of misfortune does not befall all girls, many girls experience greater difficulties with asthma at the onset of their puberty than they did at younger ages. Asthmatic symptoms show up with greater prominence a few weeks before and after the menstruation, intensifying two or three days before the menstruation in particular.

The majority of female preadolescent asthma patients can be treated normally, but the adolescent girls require different treatment due to aggravated asthmatic symptoms. In fact, prior to puberty, males are more susceptible to asthma attacks than females, and this ration undergoes a reversal during adolescence, with the girls becoming more asthma attack-prone.

The massive level of fluctuations in the hormone levels of young girls during puberty can be used to explain their asthmatic woes. Also, their dietary habits and daily lifestyles also play a part in the matter, with them being potentially exposed to various allergens in the environment amount them, something they may not experience at older or younger ages.